Low Doses of Radiation Might Help Severe Alzheimer’s Patients

 

A new study published in the Journal of Alzheimer’s Disease showed remarkable improvements in behavior and cognition in patients with severe Alzheimer’s following low-dose radiation treatment.

Morris Freedman, M.D., scientist at Baycrest’s Rotman Research Institute, and head of the neurology division, and senior author of the study said, “The primary goal of a therapy for Alzheimer’s disease should be to improve the patient’s quality of life. We want to optimize their well-being and restore communication with family and friends to avoid social isolation, loneliness, and under-stimulation. Although the study was a small pilot and should be interpreted with caution, our results suggest that low-dose radiation therapy may successfully achieve this.”

In 2015, a case report suggested a patient in hospice with Alzheimer’s disease showed signs of improvement after being treated several times with low-dose radiation to her brain. Her cognition, speech, movement, and appetite were all improved. The patient was eventually discharged from hospice and admitted to a long-term care facility for seniors.

While high doses of radiation are known to create harmful effects on our health, low-dose radiation used in CT scans, for example, can help the body protect and repair itself.

Jerry Cuttler, Ph.D., a retired scientist of Atomic Energy in Canada, has been studying the effects of radiation on health for over 25 years. “Numerous neurological disorders, including Alzheimer’s disease, are thought to be caused in part by oxidative stress that damages all cells, including those in the brain. We have natural protection systems to combat the damage, but they become less effective as we get older. Each dose of radiation stimulates our natural protection systems to work harder – to produce more antioxidants that prevent oxidative damage, to repair more DNA damage, and to destroy more mutated cells,” he said.

In the study, four individuals suffering from severe Alzheimer’s disease were treated with three low doses of radiation spaced two weeks apart. The researchers utilized standardized tests in addition to observation to record patient changes in communication and behavior following treatment. They also collected personal artifacts such as photos, videos, and descriptions from the patients’ family members.

Within one day of the first treatment, three out of four individuals showed improvements such as increased alertness and responsiveness, recognition of loved ones, mobility, social engagement, heightened mood, and more.

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Acceletronics is an industry leader in delivering the best equipment performance and service reliability from CT Scanners and Linear Accelerators across all major brands and models. Call 610-524-3300 or visit our website: https://www.acceletronics.com.

Written by the digital marketing staff at Creative Programs & Systems: www.cpsmi.com.

Cancer Patients Can Be Protected from Radiation Using a 3D-Printed Shield

 

Cancer patients could soon be donning a personalized protection shield giving them an extra level of armor against radioactive toxicity while undergoing radiation therapy. More than 200,000 patients in the United States report injuries to healthy tissue from radiation exposure annually. A large portion of the damage occurs in the mouth and gastrointestinal tract leading to oral mucositis, esophagitis, and proctitis.

A team of researchers published a study in Advanced Science that outlines the personalized 3D-printed device that shields radiation from patients. The proof-of-concept was designed by the Brigham and Women’s Hospital, Dana-Farber Cancer Institute, Massachusetts General Hospital (MGH), and the Massachusetts Institute of Technology (MIT.)

James Byrne, M.D., Ph. D., a postdoctoral researcher at Brigham and Women’s and MIT; senior radiation oncology resident physician at Brigham and Women’s; MGH; and the Dana-Farber Cancer Institute, said their testing showed “Promising results. When we treat patients with radiation, we do our best to minimize the area of healthy tissue that receives radiation and break up treatment into small doses, but it’s a fine balance. We want to administer the most dose we can to shrink the tumor without causing damage to healthy tissue. Our goal through this project was to find an innovative solution that could offer personalized protection for patients.”

To develop the shield, several types of solid and liquid materials were used. Eventually, substances that block gamma and X-rays were chosen to reduce radiation backscatter. Custom-made designs from CT scans were produced from 3D printers. Rats and pigs were used to test the devices, focusing on whether they impacted the mouth and gastrointestinal tracts. Patients commonly experience side effects of radiation in the esophagus, small intestine, or gastrointestinal tract.

The encouraging results shows that the 3D shield successfully protects healthy tissue in the mouth and rectum of rats. In humans, the device could reduce mouth radiation by 30 percent for head and neck cancer patients. A 15-percent drop in radiation exposure could also be noted for prostate cancer patients without any dose reaction to the tumor.

Acceletronics is an industry leader in delivering the best equipment performance and service reliability from CT Scanners and Linear Accelerators across all major brands and models. Call 610-524-3300 or visit our website: https://www.acceletronics.com.

 

Written by the digital marketing staff at Creative Programs & Systems: www.cpsmi.com.