Richard Ernst, Inventor of MRI, Dies

 

Richard R. Ernst, a Swiss physical chemist, and Nobel Laureate, died on June 4. He was 87. Ernst won the Nobel Prize for inventing specific methods to analyze the chemical properties of atoms, which created the foundation of Magnetic Resonance Imaging, or MRI. He helped improve MRI sensitivity, which was first tested in the 1940s to create images of body organs. 

Born in the same city where he died, Winterthur, Ernst graduated from the federal technology institute ETH Zurich. He spent his entire career there, receiving numerous honors, including the Nobel Prize for Chemistry (1991), the Wolf Prize for Chemistry (1991), the Horwitz Prize (1991), and the Marcel Benoist Prize (1986).

In 1963, Ernst began working for Varian Associates as a scientist. During that time, he invented Fourier transform NMR, noise decoupling, and other approaches. In 1968, he returned to ETH Zurich as a lecturer, gradually working his way up to Assistant Professor in 1970, Associate Professor in 1972, and full Professor of Chemistry in 1976 and the years thereafter.

A research group dedicated to magnetic resonance spectroscopy was led by Ernst, director of the Physical Chemistry Laboratory at ETH Zurich. Two-dimensional NMR and several pulse techniques were developed by Ernst, along with magnetic resonance tomography and the NMR structure determination of biopolymers in solution. He also studied intra-molecular dynamics and retired in 1998.

Ernst was a member of the following:

-          Estonian Academy of Sciences

-          US National Academy of Sciences

-          Royal Academy of Sciences, London

-          German National Academy of Sciences Leopoldina

-          Russian Academy of Sciences,

-          Korean Academy of Science and Technology

-          Bangladesh Academy of Sciences

-          Foreign Member of the Royal Society

-          World Knowledge Dialogue Scientific Board

Ernst’s awards included:

-          John Gamble Kirkwood Medal (1989)

-          Marcel Benoist Prize (1986)

-          Wolf Prize for Chemistry (1991)

-          Louisa Gross Horowitz Price of Columbia University (1991)

-          Tadeus Reichstein Medal (2000)

-          Order of the Star of Romania (2004)

Ernst had several honorary doctorates including those from:

-          Technical University of Munich

-          EPF Lausanne

-          University of Zurich

-          University Antwerpen

-          Babes-Bolyai University

-          University Montpelier

A 2009 film called Science Plus Dharma Equals Social Responsibility was produced by Carlo Burton and takes place in Ernst’s hometown.

Survivors include his wife, Magdalena Kielholz, and their children Anna Magdalena, Katharina Elisabeth, and Hans-Martin Walter.

Acceletronics is an industry leader in delivering the best equipment performance and service reliability from CT Scanners and Linear Accelerators across all major brands and models. Call 610-524-3300 or visit our website: https://www.acceletronics.com.

 

Written by the digital marketing staff at Creative Programs & Systems: www.cpsmi.com.

Radiation Could Be Less Damaging and More Effective with Trial Drug

 

An experimental drug has shown the ability to shield healthy tissue from radiation and enhance its ability to eradicate tumors. The study is published in Science Translational Medicine by UT Southwestern scientists. The pharmaceutical, named avasopasem manganese (AVA), has already been shown to prevent acute mucositis (a condition seen in head and neck cancer patients) in clinical trials. For the drug to become a routine part of clinical care, its ability to protect healthy – not only cancerous – cells from radiation needs to be tested.

Study leader Michael Story, Ph.D., professor of radiation oncology at UTSW and member of the Harold C. Simmons Comprehensive Cancer Center’s Experimental Therapeutics Research Program, worked with colleagues to treat cancerous cells with AVA prior to exposing them to radiation. After drug treatment, the cancerous cells were not protected from radiation and appeared to respond more to the adiation than those who did not receive AVA. This was especially true when high radiation doses were administered.

In mice, cancerous cells were allowed to grow into tumors. Before radiation treatment, AVA was administered, and the tumors shrank after being treated. Some of the tumors disappeared completely. Several different tumor types (lung, pancreatic, neck, head) also experienced positive results in animal trials.

Story noted that AVA is currently being tested in phase 1 and phase 2 clinical trials. “With this drug, the radiation doses we deliver could be profoundly more effective, while at the same time contribute to protecting adjacent normal tissues,” Story said.

Acceletronics is an industry leader in delivering the best equipment performance and service reliability from CT Scanners and Linear Accelerators across all major brands and models. Call 610-524-3300 or visit our website: https://www.acceletronics.com.

 

Written by the digital marketing staff at Creative Programs & Systems: www.cpsmi.com.